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November 21.2025
2 Minutes Read

Understanding the First Human Case of H5N5 Bird Flu in the U.S.

H5N5 bird flu case related chickens in close-up view.

First Human Case of H5N5 Bird Flu Confirmed in the U.S.

In a concerning development, a Washington state resident has become the first confirmed human case of the H5N5 bird flu strain in the United States, raising questions about the potential spread and implications of this new variant. The case is particularly significant as it marks the first reported incident of human infection with this strain, which was confirmed by state health officials on November 20, 2025.

A Closer Look at the Patient and Transmission

The patient, described as an older adult with underlying health conditions, resides in Grays Harbor County on the Olympic Peninsula. Following the onset of symptoms, including high fever, confusion, and difficulty breathing, the individual was hospitalized in early November. Health officials have traced the likely source of the infection to the patient’s backyard flock of mixed domestic poultry, which had been exposed to wild birds, emphasizing the importance of biosecurity in poultry management.

What This Means for Public Health

While the Centers for Disease Control and Prevention (CDC) have classified the public risk as low—given that there has been no record of human-to-human transmission—this incident poses critical questions about avian influenza. H5N5 differs from the more notorious H5N1 strain that has stirred global concern in recent years, yet scientists are wary due to the potential for mutations. A 2024 study highlighted how a minor genetic change allowed some H5N1 strains to jump from birds to humans.

The Broader Context of Avian Influenza Outbreaks

This case occurs during a period when avian flu outbreaks are widespread in the U.S., with over 1.8 million birds affected in recent weeks due to the virus. The current surge in cases correlates with the migratory patterns of wild birds, which often facilitate the spread of the virus to domestic poultry. Washington state health authorities are now scrutinizing animal health and human exposure as part of ongoing investigations.

Moving Forward: Importance of Vigilance

Public health experts stress the necessity for vigilance. The rise in human cases of avian flu, primarily among poultry farm workers, highlights a critical need for monitoring and preventive measures. With four human cases of highly pathogenic avian influenza recorded in the U.S. this year alone, the ongoing dialogue surrounding biosecurity, careful monitoring of poultry health, and community awareness becomes ever more essential.

As this situation develops, it's crucial for those in close contact with poultry to remain informed and vigilant. With awareness and appropriate steps, the risk can be minimized, keeping both humans and their avian companions safe from future outbreaks.

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